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Evolutionary genomics of anthroponosis in Cryptosporidium.

Nature microbiology - 1 May 2019

Nader Johanna L, Mathers Thomas C, Ward Ben J, Pachebat Justin A, Swain Martin T, Robinson Guy, Chalmers Rachel M, Hunter Paul R, van Oosterhout Cock, Tyler Kevin M

Abstract excerpt

Human cryptosporidiosis is the leading protozoan cause of diarrhoeal mortality worldwide, and a preponderance of infections is caused by Cryptosporidium hominis and C. parvum. Both species consist of several subtypes with distinct geographical distributions and host preferences (that is, generalist zoonotic and specialist anthroponotic subtypes). The evolutionary processes that drive the adaptation to the human...

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PMID: 30833731
DOI: 10.1038/s41564-019-0377-x

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