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Evolutionary dynamics of bacteria in the gut microbiome within and across hosts

23 Jan 2019

Abstract excerpt

Gut microbiota are shaped by a combination of ecological and evolutionary forces. While the ecological dynamics have been extensively studied, much less is known about how species of gut bacteria evolve over time. Here, we introduce a model-based framework for quantifying evolutionary dynamics within and across hosts using a panel of metagenomic samples. We use this approach to study evolution in approximately 40...

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PMID: 30673701
DOI: 10.1371/journal.pbio.3000102

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