Low Prevalence of Gram-Positive Isolates Showing Elevated Lefamulin MIC Results during the SENTRY Surveillance Program for 2015–2016 and Characterization of Resistance Mechanisms

Abstract excerpt

This study investigated the molecular mechanisms possibly associated with non-wild-type MICs for lefamulin among staphylococci and streptococci included in the lefamulin surveillance program from 2015 to 2016. A total of 2,919 Staphylococcus aureus , 276 coagulase-negative staphylococci (CoNS), 3,923 Streptococcus pneumoniae , 389 β-hemolytic, and 178 viridans group streptococci isolates were included in the...

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