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Metagenomic sequencing at the epicenter of the Nigeria 2018 Lassa fever outbreak

3 Jan 2019

Abstract excerpt

The 2018 Nigerian Lassa fever season saw the largest ever recorded upsurge of cases, raising concerns over the emergence of a strain with increased transmission rate. To understand the molecular epidemiology of this upsurge, we performed, for the first time at the epicenter of an unfolding outbreak, metagenomic nanopore sequencing directly from patient samples, an approach dictated by the highly variable genome...

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PMID: 30606844
DOI: 10.1126/science.aau9343

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