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Article

Expressions of miR‐525‐3p and its target gene SEMG 1 in the spermatozoa of patients with asthenozoospermia

21 Dec 2018

Abstract excerpt

BACKGROUND: Semenogelin 1 (SEMG1) is an important secretory protein in spermatozoa involved in the formation of a gel matrix encasing ejaculated spermatozoa. Previous studies show that the SEMG1 gene is highly expressed in spermatozoa from patients with asthenozoospermia (AZS); however, the underlying molecular mechanisms are not yet clear. OBJECTIVES: To study the molecular mechanism of high expression of SEMG1...

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PMID: 30575326
DOI: 10.1111/andr.12573

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