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Article

Expression profile of maternal circulating microRNAs as non-invasive biomarkers for prenatal diagnosis of congenital heart defects

5 Nov 2018

Abstract excerpt

OBJECTIVE: The discovery of cell free fetal microRNAs (miRNAs) in maternal circulation has opened up novel probabilities for non-invasive prenatal diagnosis. This study aims to investigate circulating miRNAs as potential biomarkers in the serum of pregnant women with congenital heart defect (CHD) fetuses. METHOD: A total of 110 pregnant women including 50 CHD cases and 60 healthy controls were included in this...

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PMID: 30551536
DOI: 10.1016/j.biopha.2018.10.110

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