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Article

Hypoxia and connectivity in the developing vertebrate nervous system

1 Dec 2018

Abstract excerpt

The developing nervous system depends upon precise regulation of oxygen levels. Hypoxia, the condition of low oxygen concentration, can interrupt developmental sequences and cause a range of molecular, cellular and neuronal changes and injuries. The roles and effects of hypoxia on the central nervous system (CNS) are poorly characterized, even though hypoxia is simultaneously a normal component of development, a...

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PMID: 30541748
DOI: 10.1242/dmm.037127

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