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Identification of hub genes with diagnostic values in pancreatic cancer by bioinformatics analyses and supervised learning methods

14 Nov 2018

Abstract excerpt

BACKGROUND: Pancreatic cancer is one of the most lethal tumors with poor prognosis, and lacks of effective biomarkers in diagnosis and treatment. The aim of this investigation was to identify hub genes in pancreatic cancer, which would serve as potential biomarkers for cancer diagnosis and therapy in the future. METHODS: Combination of two expression profiles of GSE16515 and GSE22780 from Gene Expression Omnibus...

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PMID: 30428899
DOI: 10.1186/s12957-018-1519-y

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