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Article

Programmed death ligand 1 expression in human intrahepatic cholangiocarcinoma and its association with prognosis and CD8+ T-cell immune responses

1 Oct 2018

Abstract excerpt

Background: Agents targeting the programmed death ligand 1 (PD-L1)/programmed death receptor 1 immune checkpoint exhibited promising clinical outcomes in a variety of malignant tumors, including intrahepatic cholangiocarcinoma (ICC). However, the relationship between PD-L1 expression and CD8 + T-cell immune responses is not well defined in ICC. Patients and methods: We investigated PD-L1 expression...

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PMID: 30323667
DOI: 10.2147/cmar.s172719

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