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Article

Next-Generation Sequencing to Diagnose Suspected Genetic Disorders

3 Oct 2018

Abstract excerpt

Interview with Dr. David Adams on the use of clinical next-generation sequencing to obtain a genetic diagnosis. (06:23)Download The technologies and chemistries underlying next-generation sequencing of DNA are evolving rapidly. This review describes the three main approaches to obtaining a genetic diagnosis through next-generation sequencing, their advantages, and their limitations.

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PMID: 30281996
DOI: 10.1056/nejmra1711801

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