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Evidence for a maximum “shelf-life” of oocytes in mammals suggests that human menopause may be an implication of meiotic arrest

14 Sept 2018

Abstract excerpt

There is an ongoing debate why a trait like human menopause should have evolved. Adaptive explanations explain menopause with fitness benefits of ceasing reproduction, whereas non-adaptive explanations view it as an epiphenomenon. Here we present data in support of non-adaptive explanations of menopause suggesting a maximum shelf-life of oocytes. By analyzing the association between lifespan and age at...

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PMID: 30237413
DOI: 10.1038/s41598-018-32502-2

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