Article
Mean platelet volume and lymphocyte-to-monocyte ratio are associated with shorter progression-free survival in EGFR-mutant lung adenocarcinoma treated by EGFR tyrosine kinase inhibitor.
PloS one - 1 Jan 2018
Watanabe Kousuke, Yasumoto Atsushi, Amano Yosuke, Kage Hidenori, Goto Yasushi, Yatomi Yutaka, Takai Daiya, Nagase Takahide
Abstract excerpt
BACKGROUND: A growing body of evidence supports the role of platelets in cancer metastasis, escape from immune surveillance, and angiogenesis. Mean platelet volume (MPV), which reflects platelet turnover, is reported routinely as part of automated complete blood count. Accumulating evidence suggests that MPV is a useful biomarker in several diseases including cancer. However, its role in cancer patients receiving...
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