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Impact of next generation sequencing on our understanding of CAKUT.

Seminars in cell & developmental biology - 1 Jul 2019

Nigam Anukrati, Knoers Nine V A M, Renkema Kirsten Y

Abstract excerpt

Congenital abnormalities of the kidney and urinary tract (CAKUT) form the leading cause of pediatric end-stage renal disease. Knowledge on the molecular mechanisms that underlie CAKUT leads to the improvement of DNA diagnostics and counseling regarding prognosis and recurrence risk estimation for CAKUT patients and their relatives. Implementation of next generation sequencing in research and diagnostic settings...

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Gene Expression Regulation, Developmental
Genetic Association Studies
Genetic Predisposition to Disease
High-Throughput Nucleotide Sequencing
Kidney

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Urogenital Abnormalities

Vesico-Ureteral Reflux

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PMID: 30172048
DOI: 10.1016/j.semcdb.2018.08.013

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