Article
Correlations between metabolic texture features, genetic heterogeneity, and mutation burden in patients with lung cancer.
European journal of nuclear medicine and molecular imaging - 1 Feb 2019
Moon Seung Hwan, Kim Jinho, Joung Je-Gun, Cha Hongui, Park Woong-Yang, Ahn Jin Seok, Ahn Myung-Ju, Park Keunchil, Choi Joon Young, Lee Kyung-Han, Kim Byung-Tae, Lee Se-Hoon
Abstract excerpt
PURPOSE: This study investigated the correlations between parameters of 18F-fluorodeoxyglucose (FDG) uptake on positron emission tomography (PET) scan and indices of genetic properties, heterogeneity index (HI), and tumor mutation burden (TMB), in patients with lung cancer. METHODS: We produced 106 PET indices for each tumor site that underwent genomic analysis in a total of 176 study subjects (age, 62.0 ± 10.0...
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