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Article

Prevalence Estimates of Polycystic Kidney and Liver Disease by Population Sequencing.

Journal of the American Society of Nephrology : JASN - 1 Oct 2018

Lanktree Matthew B, Haghighi Amirreza, Guiard Elsa, Iliuta Ioan-Andrei, Song Xuewen, Harris Peter C, Paterson Andrew D, Pei York

Abstract excerpt

BACKGROUND: Estimating the prevalence of autosomal dominant polycystic kidney disease (ADPKD) is challenging because of age-dependent penetrance and incomplete clinical ascertainment. Early studies estimated the lifetime risk of ADPKD to be about one per 1000 in the general population, whereas recent epidemiologic studies report a point prevalence of three to five cases per 10,000 in the general population....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30135240
DOI: 10.1681/ASN.2018050493
PMCID: PMC6171271

Genes

ALG8
GANAB
LRP5
PKD1
PKD2
PRKCSH
SEC63

Provenance

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