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Prediction of key genes and pathways involved in trastuzumab-resistant gastric cancer

22 Aug 2018

Abstract excerpt

BACKGROUND: Trastuzumab has been prevailingly accepted as a beneficial treatment for gastric cancer (GC) by targeting human epidermal growth factor receptor 2 (HER2)-positive. However, the therapeutic resistance of trastuzumab remains a major obstacle, restricting the therapeutic efficacy. Therefore, identifying potential key genes and pathways is crucial to maximize the overall clinical benefits. METHODS: The...

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Share to Gastric Cancer Management and Outcomes
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PMID: 30134903
DOI: 10.1186/s12957-018-1475-6

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