Article
Recurrent fungal infections in a Chinese patient with CARD9 deficiency and a review of 48 cases.
The British journal of dermatology - 1 May 2019
Quan C, Li X, Shi R-F, Zhao X-Q, Xu H, Wang B, Wang X-P, Hu W-G, Cao H, Zheng J
Abstract excerpt
Deficiency of CARD9 (caspase recruitment domain-containing protein 9) has been reported in individuals with recurrent and invasive fungal infections. We report on a patient who first had Trichosporon asahii affecting the skin then Candida albicans infections involving the digestive tract and knee joint, along with elevated serum IgE. After stimulation with C. albicans, peripheral blood mononuclear cells of this...
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