Article
Identifying epidermal growth factor receptor mutation status in patients with lung adenocarcinoma by three-dimensional convolutional neural networks.
The British journal of radiology - 1 Dec 2018
Xiong Jun-Feng, Jia Tian-Ying, Li Xiao-Yang, Yu Wen, Xu Zhi-Yong, Cai Xu-Wei, Fu Ling, Zhang Jie, Qin Bin-Jie, Fu Xiao-Long, Zhao Jun
Abstract excerpt
OBJECTIVE:: Genetic phenotype plays a central role in making treatment decisions of lung adenocarcinoma, especially the tyrosine-kinase-inhibitors-sensitive mutations of the epidermal growth factor receptor (EGFR) gene. We constructed three-dimensional convolutional neural networks (CNN) to analyze underlying patterns in CT images that could indicate that EGFR gene mutation status but are invisible to human eyes....
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