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Reproduction predicts shorter telomeres and epigenetic age acceleration among young adult women

17 Jul 2018

Abstract excerpt

Evolutionary theory predicts that reproduction entails costs that detract from somatic maintenance, accelerating biological aging. Despite support from studies in human and non-human animals, mechanisms linking 'costs of reproduction' (CoR) to aging are poorly understood. Human pregnancy is characterized by major alterations in metabolic regulation, oxidative stress, and immune cell proliferation. We hypothesized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30038336
DOI: 10.1038/s41598-018-29486-4

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