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Article

Tubulin genes and malformations of cortical development.

European journal of medical genetics - 1 Dec 2018

Romaniello Romina, Arrigoni Filippo, Fry Andrew E, Bassi Maria T, Rees Mark I, Borgatti Renato, Pilz Daniela T, Cushion Thomas D

Abstract excerpt

A large number of genes encoding for tubulin proteins are expressed in the developing brain. Each is subject to specific spatial and temporal expression patterns. However, most are highly expressed in post-mitotic neurons during stages of neuronal migration and differentiation. The major tubulin subclasses (alpha- and beta-tubulin) share high sequence and structural homology. These globular proteins form...

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Source

Identifiers

PMID: 30016746
DOI: 10.1016/j.ejmg.2018.07.012

Genes

TUBB
TUBB3
TUBG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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