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The C-Type Lectin Domain Gene Family in Aedes aegypti and Their Role in Arbovirus Infection

12 Jul 2018

Abstract excerpt

Several medically important flaviviruses that are transmitted by mosquitoes have been shown to bind to the C-type lectin fold that is present in either vertebrate or invertebrate proteins. While in some cases this interaction is part of a neutralizing anti-viral immune response, many reports have implicated this as critical for successful virus entry. Despite the establishment of mosquito C-type lectin domain...

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PMID: 30002303
DOI: 10.3390/v10070367

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