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Article

Colorectal Cancer Stratification in the Routine Clinical Pathway: A District General Hospital Experience.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jul 2019

Wedden Sarah, Miller Keith, Frayling Ian M, Thomas Teresa, Chefani Alina, Miller Karolina, Hamblin Angela, Taylor Jenny C, D'Arrigo Corrado

Abstract excerpt

Colorectal cancer (CRC) has many subtypes with different prognoses and response to treatment. Patients must be characterized to access the most appropriate treatment and improve outcomes. An increasing number of biomarkers are required for characterization but are not in routine use. We investigated whether CRC can be stratified routinely within a small district general hospital to inform clinical decision making...

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Identifiers

PMID: 29985199
DOI: 10.1097/PAI.0000000000000631

Genes

BRAF
EGFR
KRAS
MLH1
MSH2
MSH6
NRAS
PMS2
PTEN

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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