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Article

An easy-to-use baseline scoring system to predict response to peginterferon alfa-2a in patients with chronic hepatitis B in resource-limited settings.

Antiviral therapy - 1 Jan 2018

Lampertico Pietro, Messinger Diethelm, Oladipupo Hameed, Bakalos Georgios, Castillo Marco, Asselah Tarik

Abstract excerpt

BACKGROUND: Approximately one-third of patients have durable responses after finite (48-week) treatment with peginterferon alfa-2a. The ability to identify patients likely to respond would be particularly useful in resource-limited settings. METHODS: Data from 1,363 peginterferon alfa-2a recipients (955 hepatitis B 'e' antigen [HBeAg]-positive and 408 -negative) in six studies were analysed. Baseline scoring...

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PMID: 29972138
DOI: 10.3851/IMP3251

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