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Article

Clinical characteristics and cytokine profiles of children with acute lower respiratory tract infections caused by human rhinovirus.

PloS one - 1 Jan 2018

Ahn Jong Gyun, Kim Dong Soo, Kim Ki Hwan

Abstract excerpt

The clinical profile of human rhinovirus (HRV) with regard to lower respiratory infections remains unclear. We analyzed the clinical features and cytokine responses of HRV isolates in children with respiratory infections. Quantitative analysis and genotyping of the HRV-positive samples from 601 nasopharyngeal aspirates (NPAs) were performed using VP4/VP2 sequencing. To compare T-helper1 (Th1) type (IFN-γ, TNF-α)...

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Identifiers

PMID: 29969445
DOI: 10.1371/journal.pone.0198624
PMCID: PMC6029759

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