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Article

The Anti-Inflammatory Activities of Propionibacterium acnes CAMP Factor-Targeted Acne Vaccines.

The Journal of investigative dermatology - 1 Nov 2018

Wang Yanhan, Hata Tissa R, Tong Yun Larry, Kao Ming-Shan, Zouboulis Christos C, Gallo Richard L, Huang Chun-Ming

Abstract excerpt

Inflammatory acne vulgaris afflicts hundreds of millions of people globally. Propionibacterium acnes, an opportunistic skin bacterium, has been linked to the pathogenesis of acne vulgaris. Our results show that a secretory Christie-Atkins-Munch-Petersen (CAMP) factor of P. acnes is up-regulated in anaerobic cultures. Mutation of CAMP factor significantly diminishes P. acnes colonization and inflammation in mice,...

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Source

Identifiers

PMID: 29964032
DOI: 10.1016/j.jid.2018.05.032

Genes

CAMP
MIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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