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Estimation of age-dependent decrease in blastocyst euploidy by next generation sequencing: development of a novel prediction model

1 Jan 2019

Abstract excerpt

BACKGROUND: We developed a model to estimate the female age-dependent decrease in blastocyst euploidy and the impact of blastocyst cohort size on the likelihood of having at least one euploid blastocyst for transfer. METHODS: Retrospective analysis of 1296 trophectoderm biopsies by next-generation sequencing analysis from 436 infertile couples undergoing intracytoplasmic sperm injection and preimplantation...

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PMID: 29962186
DOI: 10.23736/s0031-0808.18.03507-3

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