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Article

Universal screening at age 1-2 years as an adjunct to cascade testing for familial hypercholesterolaemia in the UK: A cost-utility analysis.

Atherosclerosis - 1 Aug 2018

McKay Ailsa J, Hogan Helen, Humphries Steve E, Marks Dalya, Ray Kausik K, Miners Alec

Abstract excerpt

BACKGROUND AND AIMS: Familial hypercholesterolaemia (FH) is widely underdiagnosed. Cascade testing (CT) of relatives has been shown to be feasible, acceptable and cost-effective in the UK, but requires a supply of index cases. Feasibility of universal screening (US) at age 1-2 years was recently demonstrated. We examined whether this would be a cost-effective adjunct to CT in the UK, given the current and...

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PMID: 29937236
DOI: 10.1016/j.atherosclerosis.2018.05.047

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