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Article

Genetic and maternal predictors of cognitive and behavioral trajectories in females with fragile X syndrome.

Journal of neurodevelopmental disorders - 20 Jun 2018

Del Hoyo Soriano Laura, Thurman Angela John, Harvey Danielle Jenine, Ted Brown W, Abbeduto Leonard

Abstract excerpt

BACKGROUND: Fragile X syndrome (FXS) is caused by a mutation in the FMR1 gene on the X chromosome, leading to decreased levels of FMR1 protein (FMRP), which causes the array of neuropsychological impairments that define FXS. Because FXS is an X-linked condition, fewer females display FXS and females with FXS are more mildly affected than males, on average. However, there is a considerable variability in terms of...

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Identifiers

PMID: 29925305
DOI: 10.1186/s11689-018-9240-2
PMCID: PMC6011256

Genes

FMR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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