Clinical phenotypes and outcomes of pulmonary hypertension due to left heart disease: Role of the pre-capillary component.

doi:10.1371/journal.pone.0199164

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Article

Clinical phenotypes and outcomes of pulmonary hypertension due to left heart disease: Role of the pre-capillary component.

PloS one - 1 Jan 2018

Caravita Sergio, Faini Andrea, Carolino D'Araujo Sandy, Dewachter Céline, Chomette Laura, Bondue Antoine, Naeije Robert, Parati Gianfranco, Vachiéry Jean-Luc

Abstract excerpt

BACKGROUND: In pulmonary hypertension (PH), both wedge pressure elevation (PAWP) and a precapillary component may affect right ventricular (RV) afterload. These changes may contribute to RV failure and prognosis. We aimed at describing the different haemodynamic phenotypes of patients with PH due to left heart disease (LHD) and at characterizing the impact of pulmonary haemodynamics on RV function and outcome...

Topics

Adult
Aged
Biomarkers
Calcium
Capillaries
Cardiac Catheterization
Endothelium, Vascular
Female
Heart Failure
Heart Ventricles
Hemodynamics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Hypertension, Pulmonary

Kaplan-Meier Estimate

Male

Middle Aged

Natriuretic Peptide, Brain

Peptide Fragments

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Open in PubMed Open full text

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PMID: 29920539
DOI: 10.1371/journal.pone.0199164
PMCID: PMC6007912

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