Article
Diversity of rotavirus strains circulating in children under five years of age who presented with acute gastroenteritis before and after rotavirus vaccine introduction, University Teaching Hospital, Lusaka, Zambia, 2008-2015.
Vaccine - 12 Nov 2018
Simwaka J C, Mpabalwani Evans M, Seheri Mapaseka, Peenze Ina, Monze Mwaka, Matapo Belem, Parashar Umesh D, Mufunda Jacob, Mphahlele Jeffrey M, Tate Jacqueline E, Mwenda Jason M
Abstract excerpt
BACKGROUND: Following the introduction of rotavirus vaccine into the routine immunization schedule, the burden of rotavirus disease has significantly reduced in Zambia. Although rotavirus vaccines appear to confer good cross-protection against both vaccine and non-vaccine strains, concerns about strain replacement following vaccine implementation remain. We describe the diversity of the circulating rotavirus...
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