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Article

Genetic diversity of the human adenovirus species C DNA polymerase.

Antiviral research - 1 Aug 2018

Feghoul Linda, Mercier-Delarue Séverine, Salmona Maud, Ntsiba Nora, Dalle Jean-Hugues, Baruchel André, Klonjkowski Bernard, Richardson Jennifer, Simon François, LeGoff Jérôme

Abstract excerpt

BACKGROUND: Human Adenovirus (HAdV) are responsible for severe infections in hematopoietic stem cells transplant (HSCT) recipient, species C viruses being the most commonly observed in this population. There is no approved antiviral treatment yet. Cidofovir (CDV), a cytidine analog, is the most frequently used and its lipophilic conjugate, brincidofovir (BCV), is under clinical development. These drugs target the...

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PMID: 29842914
DOI: 10.1016/j.antiviral.2018.05.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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