Article
Whole-genome sequencing and analyses identify high genetic heterogeneity, diversity and endemicity of rotavirus genotype P[6] strains circulating in Africa.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2018
Nyaga Martin M, Tan Yi, Seheri Mapaseka L, Halpin Rebecca A, Akopov Asmik, Stucker Karla M, Fedorova Nadia B, Shrivastava Susmita, Duncan Steele A, Mwenda Jason M, Pickett Brett E, Das Suman R, Jeffrey Mphahlele M
Abstract excerpt
Rotavirus A (RVA) exhibits a wide genotype diversity globally. Little is known about the genetic composition of genotype P[6] from Africa. This study investigated possible evolutionary mechanisms leading to genetic diversity of genotype P[6] VP4 sequences. Phylogenetic analyses on 167 P[6] VP4 full-length sequences were conducted, which included six porcine-origin sequences. Of the 167 sequences, 57 were newly...
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