Article
Assessment of rosacea symptom severity by genome-wide association study and expression analysis highlights immuno-inflammatory and skin pigmentation genes.
Human molecular genetics - 1 Aug 2018
Aponte Jennifer L, Chiano Mathias N, Yerges-Armstrong Laura M, Hinds David A, Tian Chao, Gupta Akanksha, Guo Cong, Fraser Dana J, Freudenberg Johannes M, Rajpal Deepak K, Ehm Margaret G, Waterworth Dawn M
Abstract excerpt
Rosacea is a common, chronic skin disease of variable severity with limited treatment options. The cause of rosacea is unknown, but it is believed to be due to a combination of hereditary and environmental factors. Little is known about the genetics of the disease. We performed a genome-wide association study (GWAS) of rosacea symptom severity with data from 73 265 research participants of European ancestry from...
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