Detection of Bacteriophage Particles Containing Antibiotic Resistance Genes in the Sputum of Cystic Fibrosis Patients

Abstract excerpt

Cystic fibrosis (CF) is a chronic disease in which the bacterial colonization of the lung is linked to an excessive inflammatory response that leads to respiratory failure. The microbiology of CF is complex. Staphylococcus aureus is the first bacterium colonizing the lungs in a 30% of paediatric patients. Later, a 80 % of adult CF patients develop a chronic Pseudomonas aeruginosa infection, and other...

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