Article
Linking cervicovaginal immune signatures, HPV and microbiota composition in cervical carcinogenesis in non-Hispanic and Hispanic women.
Scientific reports - 15 May 2018
Łaniewski Paweł, Barnes Dominique, Goulder Alison, Cui Haiyan, Roe Denise J, Chase Dana M, Herbst-Kralovetz Melissa M
Abstract excerpt
While high-risk human papillomavirus (HPV) infection is a well-established risk factor for cervical cancer, there are likely other factors within the local microenvironment that contribute to cervical carcinogenesis. Here we investigated relationships between HPV, vaginal pH, vaginal microbiota (VMB) composition, level of genital immune mediators and severity of cervical neoplasm. We enrolled women with low- and...
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