Article
Ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin for chronic hepatitis C virus genotype 1b-infected cirrhotics (TURQUOISE-IV).
European journal of gastroenterology & hepatology - 1 Sept 2018
Isakov Vasily, Paduta Dzmitry, Viani Rolando M, Enejosa Jeffrey V, Pasechnikov Viktor, Znoyko Olga, Ogurtsov Pavel, Bogomolov Pavel O, Maevskaya Marina V, Chen Xiaotian, Shulman Nancy S
Abstract excerpt
OBJECTIVE: An estimated 336 per 100 000 people in Russia are infected with hepatitis C virus, including up to 75% with genotype (GT) 1b. In the TURQUOISE-II/-III trials, a 12-week regimen of the direct-acting antiviral agents ombitasvir (OBV), paritaprevir (PTV), ritonavir, and dasabuvir (DSV) in GT1b-infected patients with compensated cirrhosis resulted in 12-week sustained virologic response (SVR) rates of...
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