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Article

Conditional genetic screen in Physcomitrella patens reveals a novel microtubule depolymerizing-end-tracking protein.

PLoS genetics - 1 May 2018

Ding Xinxin, Pervere Leah M, Bascom Carl, Bibeau Jeffrey P, Khurana Sakshi, Butt Allison M, Orr Robert G, Flaherty Patrick J, Bezanilla Magdalena, Vidali Luis

Abstract excerpt

Our ability to identify genes that participate in cell growth and division is limited because their loss often leads to lethality. A solution to this is to isolate conditional mutants where the phenotype is visible under restrictive conditions. Here, we capitalize on the haploid growth-phase of the moss Physcomitrella patens to identify conditional loss-of-growth (CLoG) mutants with impaired growth at high...

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Identifiers

PMID: 29746462
DOI: 10.1371/journal.pgen.1007221
PMCID: PMC5944918

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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