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Acquisition of virulence genes by a carrier strain gave rise to the ongoing epidemics of meningococcal disease in West Africa

7 May 2018

Abstract excerpt

Significance Historically, Neisseria meningitidis serogroup A strains have caused large epidemics of meningitis across sub-Saharan Africa. Following mass vaccination from 2010, serogroup A outbreaks have been mostly eliminated. Starting in 2013 however, yearly epidemics of a previously unknown serogroup C strain have led to tens of thousands of cases in Nigeria and Niger. We show how this new strain evolved from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29735685
DOI: 10.1073/pnas.1802298115

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