Article
Microbial eukaryotes have adapted to hypoxia by horizontal acquisitions of a gene involved in rhodoquinone biosynthesis.
eLife - 26 Apr 2018
Stairs Courtney W, Eme Laura, Muñoz-Gómez Sergio A, Cohen Alejandro, Dellaire Graham, Shepherd Jennifer N, Fawcett James P, Roger Andrew J
Abstract excerpt
Under hypoxic conditions, some organisms use an electron transport chain consisting of only complex I and II (CII) to generate the proton gradient essential for ATP production. In these cases, CII functions as a fumarate reductase that accepts electrons from a low electron potential quinol, rhodoquinol (RQ). To clarify the origins of RQ-mediated fumarate reduction in eukaryotes, we investigated the origin and...
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