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Article

A role for collagen type IV in cardiovascular disease?

American journal of physiology. Heart and circulatory physiology - 1 Sept 2018

Steffensen L B, Rasmussen L M

Abstract excerpt

Over the past decade, studies have repeatedly found single-nucleotide polymorphisms located in the collagen ( COL) 4A1 and COL4A2 genes to be associated with cardiovascular disease (CVD), and the 13q34 locus harboring these genes is one of ~160 genome-wide significant risk loci for coronary artery disease. COL4A1 and COL4A2 encode the α1- and α2-chains of collagen type IV, a major component of basement membranes...

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Identifiers

PMID: 29677463
DOI: 10.1152/ajpheart.00070.2018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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