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Article

HOXC 10 promotes proliferation and invasion and induces immunosuppressive gene expression in glioma

20 Apr 2018

Abstract excerpt

The prognosis for patients with malignant glioma is very poor and thus the identification of new potential therapeutic targets is critically important. In this work, we report a previously unknown role for the homeobox transcription factor HOXC10 in regulating immunosuppressive gene expression in glioma cell lines and their proliferative and invasive capacities. Although HOXC10 expression is dysregulated in...

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PMID: 29676849
DOI: 10.1111/febs.14476

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