Article
The interplay between oral microbiome, lifestyle factors and genetic polymorphisms in the risk of oral squamous cell carcinoma.
Carcinogenesis - 28 May 2018
Hsiao Jenn-Ren, Chang Chan-Chi, Lee Wei-Ting, Huang Cheng-Chih, Ou Chun-Yen, Tsai Sen-Tien, Chen Ken-Chung, Huang Jehn-Shyun, Wong Tung-Yiu, Lai Yu-Hsuan, Wu Yuan-Hua, Hsueh Wei-Ting, Wu Shang-Yin, Yen Chia-Jui, Chang Jang-Yang, Lin Chen-Lin, Weng Ya-Ling, Yang Han-Chien, Chen Yu-Shan, Chang Jeffrey S
Abstract excerpt
Poor oral hygiene may lead to overgrowth of pathogenic oral bacteria, which may induce chronic inflammation to promote the oncogenesis of oral squamous cell carcinoma (OSCC). This study investigated the association between oral bacterial profile and OSCC risk in a case-control study of 138 OSCC cases and 151 controls (88 cases and 90 controls for the discovery group and 50 cases and 61 controls for the validation...
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