Article
Genome editing for the treatment of tumorigenic viral infections and virus-related carcinomas.
Frontiers of medicine - 1 Oct 2018
Yu Lan, Tian Xun, Gao Chun, Wu Ping, Wang Liming, Feng Bei, Li Xiaomin, Wang Hui, Ma Ding, Hu Zheng
Abstract excerpt
Viral infections cause at least 10%-15% of all human carcinomas. Over the last century, the elucidation of viral oncogenic roles in many cancer types has provided fundamental knowledge on carcinogenetic mechanisms and established a basis for the early intervention of virus-related cancers. Meanwhile, rapidly evolving genome-editing techniques targeting viral DNA/RNA have emerged as novel therapeutic strategies...
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