Article
Association of T/A polymorphism in miR-1302 binding site in CGA gene with male infertility in Isfahan population.
Molecular biology reports - 1 Aug 2018
Jamalvandi Mina, Motovali-Bashi Majid, Amirmahani Farzane, Darvishi Parisa, Jamshidi Goharrizi Kiarash
Abstract excerpt
Infertility occurs in 10-15% of couples worldwide and close to half of it is caused by male factors. One of the genes that can affect male infertility is CGA. Polymorphisms in CGA gene may affect gene expression, therefore affecting male infertility by disrupting the regulation of this gene. One of the polymorphisms is the substitution of T with A in the miR-1302 binding site in the 3' untranslated region of the...
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