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Article

Population Genomics of Francisella tularensis subsp. holarctica and its Implication on the Eco-Epidemiology of Tularemia in Switzerland.

Frontiers in cellular and infection microbiology - 1 Jan 2018

Wittwer Matthias, Altpeter Ekkehard, Pilo Paola, Gygli Sebastian M, Beuret Christian, Foucault Frederic, Ackermann-Gäumann Rahel, Karrer Urs, Jacob Daniela, Grunow Roland, Schürch Nadia

Abstract excerpt

Whole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., restriction enzyme length polymorphism typing, multi locus sequence typing etc.) is inadequate to elucidate complex disease transmission patterns, as well as resolving the phylogeny at high...

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PMID: 29623260
DOI: 10.3389/fcimb.2018.00089
PMCID: PMC5875085

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