Article
Unraveling Interactions between the Microbiome and the Host Immune System To Decipher Mechanisms of Disease
5 Mar 2018
Abstract excerpt
In recent years, there has been a deluge of papers linking altered microbiome compositions to a myriad of diseases. Mechanistic insight into microbial drivers of disease phenotypes is essential for translation to novel therapies. A key mechanism by which microbes influence health is immune modulation by components of their capsule and cell envelope and their metabolites. A major research focus of my laboratory is...
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