Article
Genotypic and Phenotypic Characterization of the O-Linked Protein Glycosylation System Reveals High Glycan Diversity in Paired Meningococcal Carriage Isolates.
Journal of bacteriology - 15 Aug 2018
Børud Bente, Bårnes Guro K, Brynildsrud Ola Brønstad, Fritzsønn Elisabeth, Caugant Dominique A
Abstract excerpt
Species within the genus Neisseria display significant glycan diversity associated with the O-linked protein glycosylation (pgl) systems due to phase variation and polymorphic genes and gene content. The aim of this study was to examine in detail the pgl genotype and glycosylation phenotype in meningococcal isolates and the changes occurring during short-term asymptomatic carriage. Paired meningococcal isolates...
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