Liver transplantation for locally advanced intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: a prospective case-series.

doi:10.1016/S2468-1253(18)30045-1

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Article

Liver transplantation for locally advanced intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: a prospective case-series.

The lancet. Gastroenterology & hepatology - 1 May 2018

Lunsford Keri E, Javle Milind, Heyne Kirk, Shroff Rachna T, Abdel-Wahab Reham, Gupta Nakul, Mobley Constance M, Saharia Ashish, Victor David W, Nguyen Duc T, Graviss Edward A, Kaseb Ahmed O, McFadden Robert S, Aloia Thomas A, Conrad Claudius, Li Xian C, Monsour Howard P, Gaber A Osama, Vauthey Jean-Nicolas, Ghobrial R Mark

Abstract excerpt

BACKGROUND: At present, intrahepatic cholangiocarcinoma is a contraindication for liver transplantation. However, previous studies in this field did not preselect patients on the basis of chemosensitivity or disease trajectory after neoadjuvant therapy. Experience with hilar cholangiocarcinoma has indicated that neoadjuvant therapy followed by liver transplantation in patients without disease progression results...

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PMID: 29548617
DOI: 10.1016/S2468-1253(18)30045-1

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