Article
Distinct genetic profiles of Leishmania (Viannia) braziliensis associate with clinical variations in cutaneous-leishmaniasis patients from an endemic area in Brazil.
Parasitology - 1 Aug 2018
Quaresma Patrícia Flávia, de Brito Cristiana Ferreira Alves, Rugani Jeronimo Marteleto Nunes, Freire Janaína de Moura, Baptista Rodrigo de Paula, Moreno Elizabeth Castro, Gontijo Raquel Carvalho, Rego Felipe Dutra, Diniz Joaquim Edemilson, Melo Maria Norma, Gontijo Célia Maria Ferreira
Abstract excerpt
American tegumentary leishmaniasis (ATL) samples obtained from the lesions of patients with typical (n = 25, 29%), atypical (n = 60, 69%) or both (n = 2%) clinical manifestations were analysed by multilocus enzyme electrophoresis, hsp70 restriction-fragment length polymorphism (PCR-RFLP), hsp70 sequencing and phylogenetics methods. The hsp70 PCR-RFLP analysis revealed two different profiles whose the most samples...
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