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Article

Fluctuations in airway bacterial communities associated with clinical states and disease stages in cystic fibrosis

9 Mar 2018

Abstract excerpt

Bacteria that infect the airways of persons with cystic fibrosis (CF) include a group of well-described opportunistic pathogens as well as numerous, mainly obligate or facultative anaerobic species typically not reported by standard sputum culture. We sequenced the V3-V5 hypervariable region of the bacterial 16S rRNA gene in DNA derived from 631 sputum specimens collected from 111 CF patients over 10 years. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29522532
DOI: 10.1371/journal.pone.0194060

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